Combining NEFL or GFAP with demographic data and cognitive tests Dementia risk linked to blood-protein imbalance in middle age
Nearly 80% of the adult population in Sweden and 57% to 80% of adults in the The elderly population worldwide is increasing, causing growing concern for age-related diseases like dementia
93), or the risk of moderate cognitive impairment in Alzheimer's dementia (HR = 0
These include: Increased risk of bone fracture in people taking higher Newly discovered mechanism can explain increased risk of dementia
htm Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach
pylori PPIs have been associated with an increased risk of a number of adverse effects including osteoporotic-related fractures, Clostridium difficile infection, community-acquired pneumonia, vitamin B12 deficiency, kidney disease, and dementia, demonstrated by a number of case-control, cohort studies, and meta-analyses
People who took these drugs for nearly 4
05) was observed for omeprazole in 7 tests for lansoprazole and pantoprazole at 5, for rabeprazole at 4
A recent study suggests that omeprazole, a common acid Northuis C, Bell E, Lutsey P, et al
Acid reflux happens when a muscle in the lower end of the A significant decrease (p < 0
Because cardiovascular risk factors and cardiovascular disease increase risk for dementia, this means that long-term PPI use probably occurs more Pantoprazole is a proton pump inhibitor (PPI)
The latest study to confirm this connection came out New research suggests that long-term use of some acid reflux drugs could increase your risk of developing dementia by as much as 33%
Some prospective studies have noticed that PPI use was associated with increased dementia risk
Phase IV trials are used to detect adverse drug outcomes and monitor drug Eight studies found no link between PPIs and dementia
Long-term use may be associated with magnesium and vitamin B12 deficiency and an increased risk of bone fracture
32), respectively, indicating that the longer women were on PPI therapy, the higher the risk of hip fracture
Common side effects of PPIs include headache and diarrhea
The authors concluded: "Thus, the avoidance of PPI medication may contribute to the prevention of dementia
People 45 and up who took PPIs for over four years had a 33% higher risk of developing dementia than people who never took the drugs, according to a study published Wednesday in the journal Neurology
Medicines to treat heartburn, also called gastroesophageal reflux disease (GERD), work by suppressing stomach acid
Design: retrospective cohort study, follow-up (years): 5 Proton pump inhibitors (PPIs) are commonly prescribed for treatment of acid-related gastrointestinal disorders
Previous studies gave conflicting Studies on the association between proton pump inhibitor (PPI) use and dementia report mixed results and do not examine the impact of cumulative PPI use
Some experimental 18 and clinical 19 studies in recent years have found that proton pump inhibitors (PPIs) are associated with an increased risk of dementia and
People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who
Sample characteristics of omeprazole users and nonusers for Cox regression
Long-Term Acid Reflux Medication Use May Increase Dementia Risk by 33% Lutsey and her colleagues analyzed healthcare data from 5,712 people with an
Proton pump inhibitors (PPIs) are widely used for the
The elderly population worldwide is increasing, causing growing concern for age-related diseases like dementia
The Journal of Neurology found a 33% higher risk of dementia for people who took PPIs for over four years
The study, published in the journal Nature Aging, opens new tab, is part of ongoing research from multiple teams to identify patients at risk for dementia using a
Sensitivity
32), respectively, compared with those of non-PPI use
Millions of people around the world use acid suppressants called proton pump inhibitors for conditions like heartburn, gastritis Pantoprazole is used to treat certain conditions in which there is too much acid in the stomach
They are the treatment of choice for several gastrointestinal disorders, such as peptic ulcer disease, esophagitis, gastroesophageal reflux disease, and H
Conclusions: This study, using large-scale, multi-centre health-data was unable to confirm an association between PPI use and increased
We did not observe a higher risk of dementia regarding use of this medication, whereas pantoprazole and esomeprazole increased this risk
9 (UPI) -- Long-term use of acid reflux medications called proton pump inhibitors may increase the risk of dementia, according to a new study published Wednesday
14 While incident dementia was not a primary outcome of this trial, PPIs (lansoprazole)
78, 95% CI 0
It works by decreasing the amount of acid produced by the stomach
J_art/Getty Images
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
Some prospective studies have noticed that PPI use was associated with increased dementia risk
Phase IV trials are used to detect adverse drug outcomes and monitor drug Eight studies found no link between PPIs and dementia
Long-term use may be associated with magnesium and vitamin B12 deficiency and an increased risk of bone fracture
32), respectively, indicating that the longer women were on PPI therapy, the higher the risk of hip fracture